Having flexible and cost-effective panels has allowed us to do more samples and go deeper and deeper” to detect those low, low fraction variants
I heard a rumour of “incredible uniformity” regarding Twist's Target Enrichment tools. We decided to try the Twist Exome to form our own opinions. The rumor was true! Not only was uniformity incredible, but coverage was, as well. Now we use a Twist Custom Panel tailored to the specific requirements of our patients.
Twist Custom Panels allowed us to focus on important, medically relevant genes instead of the whole genome. The panel was concise, with a simple protocol, and the cost reasonable with very good candidate variants already curated by the literature.
More NGS Resources
Twist Target Enrichment Protocol: For use with the Twist NGS Workflow
A comprehensive protocol for the enrichment of genomic DNA libraries with a 16-hour hybridization in a two day workflow
The Utility of Twist Respiratory Viral Controls for SARS-CoV-2 and Multiplexed Pathogen Detection
Technical Note NGS
Diverse respiratory virus controls for the accurate delineation between infectious agents with overlapping symptoms