定制组合产品页面 | Twist Bioscience

概述

Target Exactly What Matters

Twist Custom NGS Panels let you move beyond off-the-shelf solutions, giving you full control over what you sequence. Our proprietary design strategies, developed by expert bioinformaticians, power high-performance enrichment across DNA, RNA, and methylation applications. Target exactly what matters—with precision, flexibility, and performance built in.

Target Exactly What Matters

Twist Custom NGS Panels let you move beyond off-the-shelf solutions, giving you full control over what you sequence. Our proprietary design strategies, developed by expert bioinformaticians, power high-performance enrichment across DNA, RNA, and methylation applications. Target exactly what matters—with precision, flexibility, and performance built in.

主要优势

出色的性能

Twist double-stranded probes achieve uniform, high on-target coverage even in GC-rich and complex regions.

Straightforward customization

Easily design a panel around your unique genes, pathways, or variants through our online tools or with an expert.

Higher resolution

Capture rare variants, copy number variations (CNVs), or low-frequency events that arrays often miss.

Smarter spend

Reduce sequencing waste and cost by avoiding low-performing panels or overspending on whole genome approaches.

How does Twist make every read count? Resolution.

Traditional Barriers with Other Panels	Twist Solutions
Uneven coverage and GC bias leading to missed variants or dropouts	Precision probe synthesis ensures balanced coverage across GC-rich and complex regions, leading to fewer dropouts
Probe redundancy and off-target capture wasting reads and budget	Exon-aware, junction-spanning design captures isoforms, fusions, and hard-to-reach exons
Complex splicing and isoform diversity missed by rigid, pre-designed panels	Uniform, reproducible data reduces revalidation cycles and speeds time to confident results

Smarter Designs, Better Data

脱氧核糖核酸 (DNA)

Get the genomic data you need with a custom DNA target enrichment panel. 我们采用探针转换器技术等创新策略，确保定制组合的性能和精度达到最高水平。

开始设计

下载我们的《“白手套”DNA 提交表》

核糖核酸（RNA）

Capture transcriptomic data with a customized RNA panel - designed to capture and enrich libraries converted to cDNA. Our team utilizes novel RNA design strategies, such as exon-aware placement, to provide you with the transcriptomic insights you need.

下载我们的《“白手套”RNA 提交表》

甲基化

Capture methylation data with a custom DNA methylation panel. Twist’s novel design approach achieves high uniformity and retains the methylation pattern by printing four different probe species for each target: fully methylated, fully unmethylated, sense, and antisense probes.

下载我们的《“白手套”甲基化提交表》

听听科学家们怎么说

“

Twist 的销售人员可能会夸大 Twist 定制组合的好处，但我们没有理由质疑这些说法。直到我们亲自运行了他们的面板，我们才相信。我们最后一次运行的平均均匀度为 99.5%，这意味着您可以将平均覆盖率降到最低。我们在一次运行中所能容纳的样本数量基本上增加了一倍。

MARK DAVIS 博士

澳大利亚 PathWest 实验医学诊断基因组学部神经遗传学组科学家

“

其他公司则在削减成本的同时，更加注重提供一体化解决方案，而不是与客户合作设计定制探针，以满足他们高度特定的研究需求。Twist 逆势而上。

下载信息图表

LYDIA SMITH

加州大学伯克利分校进化遗传学实验室经理

“

借助 Twist 的定制组合，我们能够关注有医学意义的重要基因，而不是被迫处理整个基因组。这款组合非常简洁，采用的方案也非常简便。成本很合理，而且有文献中整理出的非常好的候选变异。”

Renata Pellegrino

费城研究中心技术总监，博士

* 客户体验的结果不能作为其他情况的预测。其他情况下的结果可能会有所不同。