Aaron Sato，首席科学官(CSO)

Learn how Twist Bioscience technology can advance your cell therapy research and development. Twist’s synthetic antibody and T cell receptor (TCR) discovery libraries are built using our proprietary oligo synthesis technology, ensuring complexity, diversity, and quality. These libraries include highly diverse synthetic naïve scFv and VHH antibody phage display libraries for discovery of targeting domains for CAR-T constructs as well as combinatorically assembled TCR libraries from gene fragments. In this webinar, Twist Bioscience’s CSO Aaron Sato will present several proof-of-concept studies showing how these technologies can be utilized for cell therapies.  

在人类生物学中，GPCR 普遍存在，参与代谢、炎症、神经传递和癌变等多种过程。Twist GPCR 文库系列利用所有已知的 GPCR 配体相互作用和现有的 GPCR 多样性，使得抗体研发突破现有的 GPCR 靶向小分子和抗体（仅涵盖人类 GPCRome 的 13%）。这一全人源合成文库系列包括 GPCR 2.0 scFv、GPCR 3.0 scFv 和 VHH h 重排 GPCR 文库。