Let's talk about your pipeline
Tell us where you are in your AI drug discovery journey. Our scientific team will reach out within one business day to discuss how Twist can accelerate your work.
Go from in silico design to physical characterization with Twist.
Get sequence-perfect antibodies, a suite of characterization assays, and AI-ready data in as few as 15 days.
ウェットラボ無しでAIモデルを構築できます。再現性の高いタンパク結合データと、開発適性判断用の物理化学データを短納期で取得。
Twist提供サービス
タンパク質作製、アッセイ、データ生成といった複雑な作業を外注することで、短納期でより多くの配列からモデル用のデータを入手できます。
高品質なデータセットを活用すれば、研究者はAIモデルのトレーニングと改良がスムーズにできます。Twist Express Antibodiesとハイスループット特性評価サービスを用いてモデルを検証し、最短15日で配列からデータが取得まで完了。
今すぐご注文Twistは、数千のタンパク質について、結合性および開発適性判断のための物理化学特性データを取得、AI設計配列の検証を可能にします。Twistは、AIおよび機械学習モデルに直接使用できる高品質なデータセットを目的として、臨床用抗体をベンチマークとしたカスタム形式でデータを提供します。
ご相談はこちらから
Twistは、配列をモデルへの統合に使える、データセットに結び付け、創薬・開発を支援します。プログラム設計やデータの解釈サポートもご提供します。
ご相談はこちらからWhether you’re looking for bespoke data configurations or help with MSA contracts, our team is here to help.
Why Twist
Others can only provide binding confirmation. Twist delivers the full developability picture: every
data type your AI model needs to train, rank, and advance leads to clinical validation.
Pinpoint your top-tier candidates with iso-affinity plots that visualize association and dissociation kinetics, allowing you to instantly rank binders by their KD performance.
Fast, quantitative binding data to validate your best candidates in a cellular context using high-throughput flow cytometry.
Map competitive binding relationships to identify epitope diversity and guide lead selection.
Benchmark manufacturing feasibility by quantifying monomeric purity and aggregation levels against clinically validated controls using our comprehensive suite of developability assays.
Rapidly assess developability by quantifying particle distribution to help rank order leads with onset of aggregation (Tagg).
Rapidly assess molecule robustness by quantifying thermal stability (Tm).
Detect off-target and polyspecific interactions early to de-risk downstream development. The data below are clinical controls we use for benchmarking purposes.
Plate-based screening correlated to gold-standard HIC and CIC to enable high-throughput, decision-ready insights.
Customizable assay platforms to evaluate functionality and mechanism of action across multiple cell types.
Tell us where you are in your AI drug discovery journey. Our scientific team will reach out within one business day to discuss how Twist can accelerate your work.
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