Whitepaper NGS

Uniformity and the Push for More Efficient Targeted Sequencing

When calculating the overall efficiency of targeted sequencing, uniformity and on-target rate are the two most common metrics cited. But which has a more significant contribution to the efficiency of the overall process?

Uniformity and the Push for More Efficient Targeted Sequencing

When calculating the overall efficiency of targeted sequencing, uniformity and on-target rate are the two most common metrics cited. But which has a more significant contribution to the efficiency of the overall process?

/sites/default/files/2019-11/WhitePaper_NGS_UniformityOnTarget_18Sep18_Rev1.pdf

In this White Paper you’ll learn:

 

  • The fundamental differences between uniformity (fold-80) and on-target rate


  • How the two metrics differ from one another when calculating read coverage


  • The impact that uniformity can have as a planning tool for targeted sequencing

Coverage Distribution

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Dive into the Case Study

Twist Bioscience

Twist Bioscience has developed a DNA synthesis platform that industrializes biological engineering, manufacturing synthetic DNA by “writing” the genetic code on a silicon chip. With this technology, Twist is manufacturing synthetic DNA-based products for use across industries including healthcare, industrial chemicals, agriculture, and academic research.