Cellular reprogramming for the scalable production of human cells

Advances in cellular reprogramming have opened new doors for studying human cells in health and disease, drug discovery, and the development of cell therapies. Widespread use of human-induced pluripotent stem cell (hiPSC)-derived mature cell types, however, is restricted by complex differentiation protocols and inefficient reprogramming methods.

Bit Bio is developing a platform capable of producing consistent and functional batches of every human cell type, with the help of Twist genes.

In this webinar you will:

  • Review fundamental concepts of cellular reprogramming.
  • Hear how Bit Bio’s novel gene engineering approach, opti-ox™, enables precisely controlled expression of transcription factors, and as a result, deterministic induction of a new cell identity.
  • See how Twist’s Clonal Genes and custom vector onboarding have allowed Bit Bio to streamline their molecular cloning of transcription factors required for cellular reprogramming.
  • Explore examples of different validated cell models that have been developed using this approach.