Twist Human Pangenome Panel

Among the latest advances in NGS genomics are the new pangenome references. In humans, the draft reference currently incorporates 49 telomere-to-telomere (T2T) human genomes, with plans to grow into the hundreds. To support pangenome-based assays and developments, we have designed a human pangenome spike-in panel as an expansion to our Twist Exome 2.0 panel (based on hg38) which we evaluate in this application note.

Covered in this Application Note

Pangenome Spike-In Design

High Target Enrichment Performance

Coverage for a wide range of variation patterns informed by population variation

Genes

Oligo Pools

NGS Target Enrichment Solutions

Variant Libraries

Synthetic Controls

Antibody Discovery

Twist Human Pangenome Panel

Related Resources

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