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Overview

Comprehensive Genomic Profiling (CGP)

CGP is an approach that utilizes next-generation sequencing (NGS) to assess multiple established biomarkers present within a solid tumor. CGP detects at a genomic resolution that allows identification of variant classes such as SNVs, indels, CNVs, select fusions, as well as cancer genomic signatures such as tumor mutational burden (TMB) and microsatellite instability (MSI).

The breadth of this single assay allows for a robust understanding of a tumor profile alleviating the need to use multiple tumor specific panels or different modalities of testing.

Comprehensive
Comprehensive updated biomarkers in a single assay
Includes 562 genes which incorporates all major tumor types
Can enable detection of SNV, CNV, TMB, and select fusions and MSI
clinical
Based in clinical research 
Enables research with recently updated biomarkers from tumor testing guidelines, such as ESCO, ASCO, and NCCN.
CGP is increasingly adopted for the utilization of post-therapy guidance biomarker analysis
Customizable
Customizable for your needs and sample population 
Breadth of coverage for key biomarkers
Customer centric content customization capabilities with integrated desired analysis solutions
Sequencer Agnostic Workflow
Tumor Sequencing

"At LifeStrands Genomics Australia, we rely heavily on Twist’s NGS probes and reagents across nearly all our assays... Twist’s probe design flexibility and scalability have allowed us to tailor both DNA and RNA panels that suit a wide range of solid tumours without compromising sensitivity or turnaround times. We view Twist not just as a vendor, but as a strategic partner in advancing precision oncology. ”

* The results are specific to the institution to which they were obtained. The results presented are customer-specific and should not be interpreted as indicative of performance across all institutions.

Dr. Vivek Rathi, MD MSc FRCPA
Medical Director
LifeStrands Genomics Australia
(Genoox User) 

Watch the Customer Webinar

Complete Solution Set for Solid
Tumor DNA Analysis

Sequencing

Compatible solutions to sequence on your preferred platform

Twist Oncology DNA CGP panel can be paired with our modular reagent solutions to enable platform compatibility.

 

TALK TO A SCIENTIST

Analysis Options

Analysis solutions to meet you lab’s needs

Twist offers a variety of bioinformatic solutions for CGP analysis.

 

TALK TO A SCIENTIST

Comprehensive Genomic Profiling (CGP)

CGP is an approach that utilizes next-generation sequencing (NGS) to assess multiple established biomarkers present within a solid tumor. CGP detects at a genomic resolution that allows identification of variant classes such as SNVs, indels, CNVs, select fusions, as well as cancer genomic signatures such as tumor mutational burden (TMB) and microsatellite instability (MSI).

The breadth of this single assay allows for a robust understanding of a tumor profile alleviating the need to use multiple tumor specific panels or different modalities of testing.

Comprehensive
Comprehensive updated biomarkers in a single assay
Includes 562 genes which incorporates all major tumor types
Can enable detection of SNV, CNV, TMB, and select fusions and MSI
clinical
Based in clinical research 
Enables research with recently updated biomarkers from tumor testing guidelines, such as ESCO, ASCO, and NCCN.
CGP is increasingly adopted for the utilization of post-therapy guidance biomarker analysis
Customizable
Customizable for your needs and sample population 
Breadth of coverage for key biomarkers
Customer centric content customization capabilities with integrated desired analysis solutions
Sequencer Agnostic Workflow
Tumor Sequencing

"At LifeStrands Genomics Australia, we rely heavily on Twist’s NGS probes and reagents across nearly all our assays... Twist’s probe design flexibility and scalability have allowed us to tailor both DNA and RNA panels that suit a wide range of solid tumours without compromising sensitivity or turnaround times. We view Twist not just as a vendor, but as a strategic partner in advancing precision oncology. ”

* The results are specific to the institution to which they were obtained. The results presented are customer-specific and should not be interpreted as indicative of performance across all institutions.

Dr. Vivek Rathi, MD MSc FRCPA
Medical Director
LifeStrands Genomics Australia
(Genoox User) 

Watch the Customer Webinar

Complete Solution Set for Solid
Tumor DNA Analysis

Sequencing

Compatible solutions to sequence on your preferred platform

Twist Oncology DNA CGP panel can be paired with our modular reagent solutions to enable platform compatibility.

 

TALK TO A SCIENTIST

Analysis Options

Analysis solutions to meet you lab’s needs

Twist offers a variety of bioinformatic solutions for CGP analysis.

 

TALK TO A SCIENTIST

DATA

Broad Coverage of Tumor Types

Twist’s DNA CGP panel covers a broad set of solid tumor types and associated mutations enabling a single panel to be utilized across many tissue types. For a complete listing of all genes, SNPs, and hotspots covered by the panel, please refer to the technical documents in the resources tab or click download button in the sidebar.

 

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The DNA CGP panel is designed to cover mutations such as single nucleotide variants (SNVs), Insertions and deletions (InDels), and copy number alterations and gene rearrangements. Additional genomic signatures scoring such as tumor mutational burden (TMB) and  microsatellite instability (MSI) is available when combined with Twist’s bioinformatic analysis solution, or a 3rd party analysis software.

Want to see what’s included in the panel?

Click the button below to download the contents of this panel including the genes covered.

Download

Broad Coverage of Tumor Types

Twist’s DNA CGP panel covers a broad set of solid tumor types and associated mutations enabling a single panel to be utilized across many tissue types. For a complete listing of all genes, SNPs, and hotspots covered by the panel, please refer to the technical documents in the resources tab or click download button in the sidebar.

 

alt

 

The DNA CGP panel is designed to cover mutations such as single nucleotide variants (SNVs), Insertions and deletions (InDels), and copy number alterations and gene rearrangements. Additional genomic signatures scoring such as tumor mutational burden (TMB) and  microsatellite instability (MSI) is available when combined with Twist’s bioinformatic analysis solution, or a 3rd party analysis software.

Want to see what’s included in the panel?

Click the button below to download the contents of this panel including the genes covered.

Download

ORDERING

Twist Oncology - DNA CGP Panel - 2.4 Mb

Product SKUs

116352

Twist Oncology DNA CGP Panel, 2.4 Mb, 2 Reactions

116353

Twist Oncology DNA CGP Panel, 2.4 Mb, 12 Reactions

116359

Twist Oncology DNA CGP Panel, 2.4 Mb, 96 Reactions

Twist Oncology - DNA CGP Panel - 2.4 Mb

Product SKUs

116352

Twist Oncology DNA CGP Panel, 2.4 Mb, 2 Reactions

116353

Twist Oncology DNA CGP Panel, 2.4 Mb, 12 Reactions

116359

Twist Oncology DNA CGP Panel, 2.4 Mb, 96 Reactions
resources

 

 

 

 

 

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Learn how leading researchers are leveraging tools built on synthetic DNA to advance their research in cancer model development, drug discovery, diagnostics, and more.

 

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Related products

Twist products are for research use only. The products presented here are not intended for the diagnosis, prevention, or treatment of a disease or condition. Twist Bioscience assumes no liability regarding use of the product for applications in which it is not intended. The results are specific to the institution to which they were obtained. The results presented are customer-specific and should not be interpreted as indicative of performance across all institutions.

One easy workflow for ultra-high throughput
One easy workflow for ultra-high throughput
One easy workflow for ultra-high throughput