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Pushing the Boundaries of High Sensitivity Epigenetic Applications
DNA methylation is an essential epigenetic modification that influences the control of gene expression. Anomalies in this process can lead to genomic instabilities or issues with transcriptional silencing, which can result in various diseases such as cancer, diabetes, cardiovascular disease, and various inflammatory conditions.
Scientists must therefore access the right tools to effectively study a given sample’s DNA methylation status and better understand genome-wide methylation patterns.
Covered in this Article
The limitations of traditional methylation-sequencing workflows
Improving methyl-seq with enzymatic conversion and target enrichment probe design
Twist Bioscience's innovative NGS methylation detection system
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