Development of a High-Throughput Target Enrichment System

Presented at AGBT 2019: Development of a robust multiplexing foundation with fast hybridization for one-day sequencing pipelines

The potential to utilize target enrichment for large-scale genomic analysis has grown with the increased capacity and availability of next-generation sequencing instruments. Described here is the development of a systematic approach to better utilize the capacity of sequencing instruments by decreasing processing time and increasing the throughput of target enrichment while maintaining high performance.