Many methods exist to generate variant libraries, but they generally have significant drawbacks and limitations, including lack of codon control, sequence biases, and incomplete generation of desired variants. Twist Bioscience Site Saturation Variant Libraries leverage massively parallel oligonucleotide synthesis using a silicon-based DNA synthesis platform and extensive molecular biology expertise to systematically and precisely construct variant libraries. Twist libraries are NGS-verified to confirm that all desired variants are present in the correct ratios. Read the product sheet to learn more.