Twist GPCR Library Series

Unlock the G-protein coupled receptor (GPCR) interactome for antibody discovery

GPCRs are ubiquitous in human biology, participating in diverse processes such as metabolism, inflammation, neurotransmission, and carcinogenesis. The Twist GPCR Library Series leverages all known GPCR-ligand interactions and existing GPCR antibody diversities to enable antibody discovery beyond existing GPCR-targeting small molecules and antibodies, which cover only 13% of the human GPCRome. This fully human synthetic library series includes the GPCR 2.0 scFv, GPCR 3.0 scFv, and VHH hShuffle GPCR libraries.

Genes

Oligo Pools

NGS Target Enrichment Solutions

Variant Libraries

Synthetic Controls

Antibody Discovery

Twist GPCR Library Series

Related Resources

Writing the Future of Biologics using the Twist Biopharma Library of Libraries

Discover Antibody Candidates Against a Panel of Hard-to-Drug GPCR Targets

Writing the Future of Biologics to Discover and Optimize Antibodies