Comparison data of Twist Exome 2.0 panels with a selection of four commercially available exome panels

Population genomics studies are uniquely suited to identifying rare and polygenic patterns in the human genome, shining valuable light on both the genetic drivers of disease and our complex evolutionary history. Such studies have traditionally relied on data collected using either microarrays or low-pass whole genome sequencing (lpWGS). Though valuable, the genetic content of these assays may not be easily customized and can result in poor coverage over key variants (thereby affecting assay sensitivity). As a result, the breadth of insights gained from population genomics studies is severely limited by these tools.


Covered in this Article
Demonstration of superior uniformity for Twist Exomes 2.0
Comparisons on the levels of achievable depth of coverage
Performance comparison when targeting of clinically relevant genes
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