BEAT 2.0 – Ichnos’ Next Generation Bi- and Multi-specific Antibody Platform

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Presented by
Carole Estoppey
Carole Estoppey
Ichnos Sciences

Covered in this Webinar
The Bispecific Engagement by Antibodies based on the T-cell receptor (BEAT) platform that Ichnos has developed
How Ichnos is addressing potential light chain mispairing with common light chain (cLc) technology
How Twist DNA synthesis and cloning enables efficient and fast combination of VHs and Fc fragments

Ichnos is currently evaluating two T cell engagers in clinical trials that are based on the BEAT® 1.0 bispecific antibody (bsAb) platform (Bispecific Engagement by Antibodies based on the T-cell receptor). To further improve the platform and in particular increase the ease of scalability, the Ichnos’ BEAT® 2.0 next generation bsAb platform addresses potential light chain mispairing with common light chain (cLc) technology. We have generated a range of multispecific antibodies having the potential to tackle more complex molecular and cellular mechanisms whilst maintaining favorable developability profiles.

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