Collaborating for Cocktails: The Coronavirus Immunotherapeutics Consortium (CoVIC)

Collaborating for Cocktails: The Coronavirus Immunotherapeutics Consortium (CoVIC)

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Presented by
Sharon Schendel
Sharon Schendel
La Jolla Institute for Immunology
RECORDED AT Writing the Future of Infectious Disease

Covered in this Webinar
Analysis by seven partner labs of antibody features
A publicly available database (CoVIC-DB) that allows analysis of relationships among antibody features

"The Coronavirus Immunotherapeutic Consortium (CoVIC) is an international effort to conduct side-by-side comparisons of therapeutic antibody candidates against SARS-CoV-2 spike originating from multiple sources, such as COVID-19 survivors and in silico design. 
Covered in this webinar:
Analysis by seven partner labs of antibody features including in vivo protection, spike protein affinity, epitope binning, blockage of ACE-2 binding, neutralization of pseudovirus and authentic virus infection, risk of mutagenic escape, and Fc-mediated functions. 
A publicly available database (CoVIC-DB) that allows analysis of relationships among antibody features and can inform selection of potent antibody therapies that are resistant to viral mutagenic escape.   

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