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Webinar
Twist Bioscience HQ
681 Gateway Blvd
South San Francisco, CA 94080
Improved mutation detection with targeted sequencing
Detecting known and novel mutations in a host's SARS-CoV-2 population by ultra-deep sequencing with unique molecular barcodes
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Hear about about benchmarking of various approaches for complete sequencing of the SARS-CoV-2 genome
Viruses mutate rapidly and hundreds of mutations have been detected in the SARS-CoV-2 genome, some of which can increase infection rates as recently reported for the novel strain B1.1.7. Novel mutations can also affect the accuracy of diagnostic tests, the efficiency of vaccines, and may associate with clinically relevant phenotypes (disease severity, response to treatment).
Viral whole genome sequencing can readily reveal novel mutations and thereby contribute to an improved understanding of virulence and the reconstruction of worldwide transmission routes.
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