Next generation CRISPR screens based on single-cell transcriptomics

Combining CRISPR screening and single cell transcriptomics to enable genetic screening for complex phenotypes.

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Learn how Aelian uses CROP-seq to move beyond the more simplistic screening read outs.

How the approach can map known signaling pathways and assess the impact of regulators on transcription.

A comparison of the feasibility of both unbiased and targeted single-cell RNA sequencing

Understand the importance of uniform oligo pools to ensure screening success.

On April 21st, 2020 Twist hosted Dr. Tilmann Buerckstuemmer, CSO of Aelian Biotechnology, who spoke about leveraging two transformative technologies - CRISPR screening and single cell transcriptomics - to enable genetic screening for complex phenotypes.

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Genes

Oligo Pools

NGS Target Enrichment Solutions

Variant Libraries

Synthetic Controls

Antibody Discovery

Next generation CRISPR screens based on single-cell transcriptomics

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