Targeted Epigenome Sequencing of cfDNA to Improve Sensitivity for Early Cancer Detection

Discover how the Cancer Research UK early detection program engaged with the Twist Targeted Methylation Sequencing Alpha Program to enable the analysis of cancer markers in cell-free DNA

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The research groups philosophy on early cancer detection

A pipeline for the identification of methylation without destructive bisulfite sequencing

How the Twist solution outperforms competitors in their application

Gahee Park, PhD, from the University of Cambridge shares how DNA methylation changes are robust cancer-specific markers and how Twist Targeted Methylation solution helped her team achieve higher than previous results — including three times better for enrichment and four times less expensive than other products used previously.

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Genes

Oligo Pools

NGS Target Enrichment Solutions

Variant Libraries

Synthetic Controls

Antibody Discovery

Targeted Epigenome Sequencing of cfDNA to Improve Sensitivity for Early Cancer Detection

Related Resources

Highly Sensitive Methylation Detection Using Enzymatic Methyl-seq and Twist Target Enrichment

Twist Targeted Methylation Sequencing Protocol

NGS Methylation Detection System