2022 Technology Focus report developed by the Institutes of Science and Development, Chinese Academy of Sciences (CASISD), is based on the role of "Technology Focus" in the fields of information, energy, life and material manufacturing in the new technological revolution. We select and determine "20 High-impact Patented Technology Focus" from the 32 "Technology Focus" areas that are highlighted in the report. It briefly describes the basic meaning, technological innovation challenges, and the research path. Based on the distribution of comprehensive influence scores of patent data in "Technology Focus", it reveals the technical innovation points and the characteristics of the national institutions of the patents with higher scores. Finally, three conclusions are given:(1) the technology focus characterizes the "difficulties" and "pain points" of industrial technological innovation in many fields around the world; (2) developed countries in science and technology occupy the commanding heights of most "Technology Focus"; and (3) the patent patent ownership institutions in the "Technology Focus" are leaders in industrial technological innovation.