Iterate AI models without wet-lab bottlenecks. Get reproducible binding and developability data in as few as 15 days.
How Twist can help
Generate more sequences, move faster, and get model-ready data without taking on the complexity of protein production, assay execution, or data generation.
Twist connects sequence generation to documented,
model-ready data through an integrated suite of products and services.
Input your sequences from your Gen AI platforms to generate DNA or protein production for wet-lab validation.
Order now
With high-quality datasets, researchers can train and refine their AI models. Validate those models with Twist Express Antibodies and high-throughput characterization services to generate data from sequences in as few as 15 days.
Order nowTwist enables the validation of your AI outputs for thousands of proteins for binding and developability characteristics. Twist offers custom data delivery formats that are benchmarked against clinical antibody controls to ensure high-quality datasets ready for direct use in your AI and machine learning models.
Speak to an expert
Twist connects your sequences to documented and predictable data sets that you can use to integrate into your models improve your drug discovery and development efforts. Need help designing a program or interpreting your data?
Speak to an expertWhether you’re looking for bespoke data configurations or help with MSA contracts, our team is here to help.
Why Twist
Others can only provide binding confirmation. Twist delivers the full developability picture: every
data type your AI model needs to train, rank, and advance leads to clinical validation.
Pinpoint your top-tier candidates with iso-affinity plots that visualize association and dissociation kinetics, allowing you to instantly rank binders by their KD performance./p>
Fast, quantitative binding data to validate your best candidates in a cellular context using high-throughput flow cytometry.
Map competitive binding relationships to identify epitope diversity and guide lead selection.
Benchmark manufacturing feasibility by quantifying monomeric purity and aggregation levels against clinically validated controls using our comprehensive suite of developability assays.
Rapidly assess developability by quantifying particle distribution to help rank order leads with onset of aggregation (Tagg).
Rapidly assess molecule robustness by quantifying thermal stability (Tm).
Detect off-target and polyspecific interactions early to de-risk downstream development. The data below are clinical controls we use for benchmarking purposes.
Plate-based screening correlated to gold-standard HIC and CIC to enable high-throughput, decision-ready insights.
Customizable assay platforms to evaluate functionality and mechanism of action across multiple cell types.
Tell us where you are in your AI drug discovery journey. Our scientific team will reach out within one business day to discuss how Twist can accelerate your work.
Not for use in diagnostic procedures.
Twist Bioscience HQ
681 Gateway Blvd
South San Francisco, CA 94080
Genes
Oligo Pools
NGS
Variant Libraries
Antibody Discovery
IVDR Solutions
