oligo pool

Oligo Pools

Twist Oligo Pools are highly diverse collections of single-stranded oligonucleotides synthesized using our silicon-based DNA writing technology. Our synthesis platform enables massively parallel production of hundreds of thousands of high-quality, accurate oligos per run.
Oligo pools are utilized in many applications including generation of CRISPR guide RNA (sgRNA) libraries, peptide screens, protein screens, and high-throughput reporter assays.
Accuracy and uniformity of oligo synthesis are critical to ensure high quality oligo libraries are built and screens are precisely targeted. Our industry-leading low synthesis error rate and uniform sequence representation result in high quality custom oligo libraries that enable the most efficient screens.

Coming Soon: seamless ecommerce, built for scientists

Seamless Ecommerce

Effortless file imports

Use your own sequence files or our templates.

Real time pricing

No more surprises when you get a quote.

Everything in a central dashboard

Track every order, project, address, and more.

Anytime optimization

Make updates at your convenience. Fully self-service!

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Finally, an easy way to order DNA


Instantly know if your sequence is a go
Our smart algorithm lets you know in seconds if your sequence can be synthesized or not

Your quote is now just one click away
No more wasted time waiting for surprise quotes. See real-time pricing when you submit your data

Stay in the know from checkout to your door
We update you at every stage of your orders’ progress, giving you comprehensive insight on crucial production details

Intuitive usability meets bulletproof security
Upload your sequences with the comfort of knowing your proprietary data is protected

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