We developed the Twist Bioscience DNA Synthesis Platform to address the limitations of throughput, scalability and cost inherent in legacy DNA synthesis methods. Applying rigorous engineering principles to harness the highly-scalable production and processing infrastructure of the semiconductor industry allows us to achieve precision in manufacturing DNA at scale. We have industrialized the production of cost-effective, high-fidelity, high-throughput DNA, which is delivered to our customers via seamless Online Ordering.
Silicon-powered DNA synthesis
Twist Bioscience developed a proprietary semiconductor-based synthetic DNA manufacturing process featuring a high-throughput silicon platform that allows us to miniaturize the chemistry necessary for DNA synthesis. This miniaturization allows us to reduce the reaction volumes by a factor of 1,000,000 while increasing throughput by a factor of 1,000, enabling the synthesis of 9,600 genes on a single silicon chip at full scale. Traditional synthesis methods produce a single gene in the same physical space using a 96-well plate.
96 Oligos = 1 Gene
OUR SILICON PLATFORM
> 1 Million Oligos = 9,600 Genes