Publications
Catalysis Science & Technology, May 2025 |
15
 (
11
),
3363-3371
 DOI:
10.1039/d4cy01367k

A highly active and regioselective cannabigerolic acid synthase engineered from a promiscuous prenyltransferase NphB

Park, Ye Seop; Kim, Minju; Na, Chae Yeong; Ham, Hyeon Woo; Cho, Jun-Young; Park, Boyoung; Jung, Cheulhee; Park, Daechan; Yoo, Tae Hyeon
Product Used
Genes
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Abstract
We report a highly active and regioselective NphB prenyltransferase variant (V49W/S214H/A232S/Y288P) to synthesize cannabigerolic acid using geranyl pyrophosphate and olivetolic acid efficiently.
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Product Used
Genes

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