Publications
Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia
Zhang, Qian;
Matuozzo, Daniela;
Le Pen, Jérémie;
Lee, Danyel;
Moens, Leen;
Asano, Takaki;
Bohlen, Jonathan;
Liu, Zhiyong;
Moncada-Velez, Marcela;
Kendir-Demirkol, Yasemin;
Jing, Huie;
Bizien, Lucy;
Marchal, Astrid;
Abolhassani, Hassan;
Delafontaine, Selket;
Bucciol, Giorgia;
COVID Human Genetic Effort, ;
Bayhan, Gulsum Ical;
Keles, Sevgi;
Kiykim, Ayca;
Hancerli, Selda;
Haerynck, Filomeen;
Florkin, Benoit;
Hatipoglu, Nevin;
Ozcelik, Tayfun;
Morelle, Guillaume;
Zatz, Mayana;
Ng, Lisa F P;
Lye, David Chien;
Young, Barnaby Edward;
Leo, Yee-Sin;
Dalgard, Clifton L;
Lifton, Richard P;
Renia, Laurent;
Meyts, Isabelle;
Jouanguy, Emmanuelle;
Hammarström, Lennart;
Pan-Hammarström, Qiang;
Boisson, Bertrand;
Bastard, Paul;
Su, Helen C;
Boisson-Dupuis, Stéphanie;
Abel, Laurent;
Rice, Charles M;
Zhang, Shen-Ying;
Cobat, Aurélie;
Casanova, Jean-Laurent
Abstract
Recessive or dominant inborn errors of type I interferon (IFN) immunity can underlie critical COVID-19 pneumonia in unvaccinated adults. The risk of COVID-19 pneumonia in unvaccinated children, which is much lower than in unvaccinated adults, remains unexplained. In an international cohort of 112 children (
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