In this chapter, we discuss the first step of converting binary data into DNA code. When we compile a program in a computer, we convert the text code into binary code (0101). The code is exactly as the original text. In DNA storage, we are doing the same. In DNA synthesis, we convert the binary data into DNA blocks (adenine, thymine, cytosine, and guanine). This is the first step in storing binary data into DNA. So, in the synthesis stage, we create DNA blocks that represent the original text. So, in DNA storage, the first step is to convert the text data into DNA code. The second step is to arrange the DNA code to the same order as the original text.