There is a growing focus in research on developing greener technologies to support the shift from a chemical-based economy to a bio-economy. This shift involves creating sustainable alternatives that reduce synthetic chemicals’ environmental footprint and health risks. Innovations in biotechnology, synthetic biology, and bioengineering drive the discovery and production of natural compounds, such as biopesticides, offering safer and more eco-friendly solutions. These technologies aim to replace conventional chemicals with biologically-derived products that are renewable, biodegradable, and less harmful to ecosystems. In order to contribute to this mission, we have employed _Physcomitrium patens_ as a photosynthetic cell factory. _P. patens_ has been shown to serve as a biological chassis to produce diverse high-value compounds. This study explores the capability of this model organism to produce pyrethrins.