GWAS in a Rat Model of Temperament Identifies Multiple Loci for Exploratory Locomotion and Anxiety-Like Traits

We probed genetic differences produced by a long-term selective breeding program by creating an F2 cross between two phenotypically divergent outbred rat lines and then used this F2 cross to map loci for the selection trait, sensation-seeking behavior, as well as several putatively correlated traits.

Covered in this Poster

Data analysis overview for SNP calling and imputation.

The significant findings of novel loci linked to behavior traits using the low-coverage WGS with Twist 96-plex Library Prep Kit.

Genes

Oligo Pools

NGS Target Enrichment Solutions

Variant Libraries

Synthetic Controls

Antibody Discovery

GWAS in a Rat Model of Temperament Identifies Multiple Loci for Exploratory Locomotion and Anxiety-Like Traits

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