Publications
Forensic science international. GeneticsOct 2024 |
74
103160
DOI:
10.1016/j.fsigen.2024.103160

The power of hybridization capture - Illustrated using an expanded gene panel on 100 post mortem samples, focusing on sudden unexplained death

Kling, Daniel; Adolfsson, Emma; Gréen, Henrik; Gréen, Anna
Product Used
NGS
Abstract
Sudden unexpected death (SUD) is an unexpected event that in many cases are caused by diseases with an underlying genetic background. Forensic molecular autopsy is an approach that has gained wide-spread attention, in part explained by the rapid progress of DNA sequencing techniques. The approach leverages genetic data in combination with medical autopsy findings in post-mortem samples to explore a potential underlying genetic cause of death. Traditional forensic approaches to molecular autopsy focus on a small panel of genes, say
Product Used
NGS

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