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Antibody Characterization

High-throughput screening to deliver you the most promising leads

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Take One Step Closer to the Clinic

Every discovery program— whether powered by in vivo, in vitro, or in silico platforms — is best complemented by experimental characterization data. Expression and comprehensive screening help ensure the best antibody candidates are selected to progress to preclinical and clinical testing.

At Twist Bioscience, we perform extensive biochemical screening and characterization that enables you to make informed decisions about which candidate to pursue. We also perform affinity testing and ranking, epitope binning, developability assessments, and purity analysis. Find out more about how these services can deliver you an antibody lead with the highest potential for preclinical and clinical success.

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High-Throughput

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Scalable

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End-to-EndBiopharma

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Customizable

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State-of-the-Art

Our Capabilities

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Biophysical Characterization

Our high-throughput technologies for antibody affinity ranking and epitope binning are driven by our biophysical experts using multiple Carterra LSA SPR platforms and other bioanalytical tools to enable the screening of thousands of antibody affinities and bin up to 192 x 192.

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Developability Assessment

It doesn’t matter if you have the most potent, efficacious biotherapeutic if it cannot produce at scale or aggregates at high concentrations. We ensure that your most developable candidates progress to downstream testing with our comprehensive assay suite.

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Functional Assays

Our scientific experts use off-the-shelf or can develop custom assays to readily assess antibody Mechanism of Action (MoA). We can perform internalization, cytotoxicity, or other functional assays on-Beacon or methods like ELISA and flow cytometry to measure biotherapeutic safety and efficacy.

Are you looking for a specific application or interested in designing a custom program with our antibody engineers?

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Antibody enthusiasts are standing by and would love to hear more about your discovery needs. Challenging targets welcome!