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Build your Workflow on Confidence

Whether you’re profiling variants, expression levels, or regulatory markers, you need workflows that deliver reliable accuracy and the flexibility to evolve with your goals. Twist provides a unified library prep and enrichment foundation built to support genomics, transcriptomics, and epigenomics.

Genomics

Precision-driven whole genomes, exomes, and targeted panels; Twist delivers engineered accuracy with uniform coverage, low bias, and reliable variant calling. With Twist, you get flexible tools for your evolving genomic needs.

 

TOOLS FOR GEMONIC WORKFLOWS

Transcriptomics

Expression confidence from start to signal; Twist delivers exon-aware performance that preserves isoforms and splice junctions. Whether you're profiling bulk RNA or targeted signatures, our modular designs provide the support your workflow needs.

TOOLS FOR TRANSCRIPTOMICS WORKFLOWS

Epigenomics

Epigenomic assays demand sensitivity and precision, and Twist delivers engineered accuracy for this. Custom methylation panels target CpG islands, enhancers, promoters, or cell specific signatures with exceptional uniformity driving consistent results.

TOOLS FOR EPIGENOMIC WORKFLOWS

NGS Workflows

Crop and Livestock Improvement

From low-pass exploration to deep coverage precision, Twist empowers researchers to execute and scale whole genome sequencing with accuracy they can trust.

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NGS Optimized Enzymes

Twist’s library prep kits use AI/ML-engineered proprietary enzymes to deliver purpose-built, reliable, and consistently superior NGS results.

Superior Performance for High Quality Data

Get more insights with Twist’s high-yield, high-complexity libraries that boost depth, cut duplicates, and improve coverage.

Flexible Workflows for Any Application

With a full range of tailored library prep kits and adapters, Twist ensures you get the data you need.

With a WES solution built on intelligently designed exome panels and optimized enrichment, Twist delivers highly uniform, on-target coverage of clinically relevant coding and noncoding regions.

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Efficient by Design

Twist exome panels focus sequencing on clinically relevant regions, improving efficiency while reducing sequencing and analysis costs.

Better Probes, Better Panels

All Twist panels use dsDNA probes engineered for consistent hybridization and uniform coverage across diverse samples.

Endlessly Adaptable

Twist Exome spike-ins boost coverage of disease-specific or custom targets, enhancing depth and performance without disrupting your workflow.

Twist’s custom DNA enrichment panels deliver tailored, high precision solutions, with expert bioinformatics support for exceptional performance.

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Exceptional, Consistent Performance

High fidelity double stranded DNA probes with NGS based quality control ensures balanced probe representation and minimizes dropout.

Panel Blending

Simplify your genomics workflow by combining two or more panels into a single, cohesive assay; either seamlessly in your own lab or with Twist handling the integration for you.

Scalable

Cover exactly the regions you need in your genomic regions of interest; with designs ranging from as few as 100 probes to well over one million.

Sustainability and Environmental Resilience

Twist RNA-Seq solutions, designed for demanding samples such as low input and FFPE so you can get high quality libraries with high yield in a short workflow so you can get results.

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Optimized RNA-Seq for Tough, Low-Input Samples

Twist RNA-Seq workflows generate high-quality, uniform libraries, ensuring reliable transcriptome coverage even with challenging material.

Rapid RNA-Seq That Doesn’t Sacrifice Quality

Twist’s fast-protocol RNA-Seq speeds library prep and turnaround while preserving coverage and data quality.

Comprehensive, fast whole-transcriptome RNA-Seq from any sample

Twist Whole Transcriptome RNA Library Prep delivers unbiased, high-quality libraries from total RNA; including FFPE, degraded, or low input sample.

RNA enrichment panels capture cDNA libraries for NGS, with exon-aware designs that deliver deeper, more informative transcription insights.

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RNA Exome Panel: More Targets, Fewer Reads

RNA Exome focuses sequencing on protein coding transcripts to enable sensitive detection of low expressing genes while preserving isoform and junction information.

RNA Fusion Panel: Confidently Enrich RNA Gene Fusions

The Twist RNA Fusion Panel Kit is an RNA based enrichment panel that enables more sensitive and targeted detection of gene fusions than conventional methods.

Custom RNA Panel: Target Exactly What Matters.

Capture transcriptomic data with a customized RNA panel; designed to capture and enrich libraries, to provide you with the transcriptomic insights you need

Therapeutic Development

Twist’s methylation sequencing delivers high quality libraries and targeted panels that preserve DNA integrity and maximize CpG recovery.

 

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High Quality, Low-Damage Libraries

Enzymatic conversion and Twist’s optimized library prep preserve DNA integrity, producing higher complexity libraries and reliable results from challenging, low input samples.

More CpGs, Better Resolution

The workflow supports detection of up to ~15% more CpGs than traditional bisulfite based methods, improving coverage of biologically important regions.

Adaptable for Existing Methyl-Seq Pipelines

Twist’s methylation library workflow fits seamlessly into standard NGS and methyl-seq pipelines without major protocol changes.

Twist’s methylation sequencing delivers high quality libraries and targeted panels that preserve DNA integrity and maximize CpG recovery.

 

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Human Methylome Panel: Broad CpG coverage

Expansive content makes this panel ideal for investigating methylation fractions across applications including cancer metastasis, human development, and functional genomics.

Twist Pan Cancer Methylation Panel

A cancer specific methylation panel, focused on methylation targets relevant to 31 different cancers.

Custom Methylation Panels: Smarter Design, Better Data

Custom DNA methylation panels enable high uniformity capture while preserving native methylation patterns through a four probe design targeting fully methylated, unmethylated, sense, and antisense sequences.

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Twist Bioscience HQ
681 Gateway Blvd
South San Francisco, CA 94080