The Twist Precision Dx Products are a suite of approved regulated solutions that support sequencing workflows for clinical applications. The Twist Precision Dx Products include a highly sensitive nucleic acid library preparation and enzymatic fragmentation kit used for the preparation of sequencing libraries from high-quality genomic DNA isolated from human cells, such as whole blood. The Twist Precision Dx Products utilize Twist Bioscience’s robust target capture system to produce target-enriched libraries compatible with Illumina sequencing instrumentation. This document provides the labeling and workflow information for the following products:

• Twist Precision Prep and Enrichment Dx Kit - The Twist Precision Prep and Enrichment Dx Kit is a reagent kit including enzymatic fragmentation, library preparation, and targeted capture. The kit is intended for use with high-quality genomic DNA derived from human cells in the preparation of libraries for Next-Generation Sequencing (NGS) applications. The kit can be used to target specific regions of the genome with DNA panels supplied by users or with a qualified Twist DNA panel (such as the Twist Precision Exome Dx Panel) for Next-Generation Sequencing (NGS) applications.
   

• Twist Precision Exome Dx Panel - The Twist Precision Exome Dx Panel is a qualified Twist DNA panel used in conjunction with the Twist Prep and Enrichment Dx Kit to produce exome-enriched libraries compatible for Next Generation Sequencing applications.
   

• Twist Precision Exome Dx Kit - Twist Precision Exome Dx Kit is a reagent kit including enzymatic fragmentation, library preparation, and targeted capture with the included Twist Precision Exome Dx panel. The kit is intended for use with high-quality genomic DNA derived from human cells. The kit utilizes the qualified Twist Precision Exome Dx Panel with the Twist Precision Prep and Enrichment Dx Kit to produce exome-enriched libraries compatible for Next-Generation Sequencing (NGS) applications.