Twist Bioscience HQ
681 Gateway Blvd
South San Francisco, CA 94080
Blood cancer discovery,
May 2025
|
6
(3),
203-216
DOI: 10.1158/2643-3230.BCD-24-0274
Dynamics of Mutant Hematopoietic Progenitor Cells Are Not Associated with Clinical Outcomes in Multiple Myeloma
Guerrero, Camila ;
Larrayoz, Maria-Jose ;
Erdozain, Irache ;
Puig, Noemi ;
Cedena, Maria-Teresa ;
Maia, Catarina ;
Mañu, Amagoia ;
Gordillo, Natalia ;
Churruca, Oihane ;
Alignani, Diego ;
Sarvide, Sarai ;
Vazquez, Iria ;
Perez, Cristina ;
Oriol, Albert ;
Rosinol, Laura ;
Ríos-Tamayo, Rafael ;
Gonzalez-Perez, Marta-Sonia ;
Gonzalez-Rodriguez, Ana-Pilar ;
de Arriba, Felipe ;
Moraleda, Jose M ;
Martin, Jesus ;
Palomera, Luis ;
Cabañas, Valentin ;
Calasanz, Maria-Jose ;
Martinez-Lopez, Joaquin ;
Mateos, Maria-Victoria ;
Bladé, Joan ;
Lahuerta, Juan-Jose ;
San-Miguel, Jesus F ;
Paiva, Bruno
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PRODUCTS USED
Variant Libraries
ABSTRACT
SPMs that develop in patients with multiple myeloma have a deleterious impact on survival. Patients with CH may be at risk of developing SPMs, which could potentially be avoided through individualized treatment. However, our results suggest that screening for CH at diagnosis has limited utility.
PRODUCTS USED
Variant Libraries
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