Recent Progress in High-Throughput Enzymatic DNA Synthesis for Data Storage

ABSTRACT

DNA has emerged as an attractive medium for storing large amounts of data due to its high information density, long-term stability, and low energy consumption. However, in contrast to commercially available storage media, DNA-based data storage currently falls behind in terms of writing and reading speeds, waste as well as cost. To harness the full potential of DNA as a data storage medium, it is imperative to advance high-throughput DNA synthesis without compromising cost and pollution. Industry-standard phosphoramidite DNA synthesis has reached its limitation because of its short nucleotide length (