Our Expertise
Tailored Solutions to Kickstart your Project
Our Twist Applications Lab provides expert support to help you conduct rapid proof-of-concept studies, optimize assays, and validate experiments. With an in-house lab optimized for high-throughput efficiency, and an expert team of laboratorians, our Applications Lab can advance your project while saving you time.
- High-quality, custom DNA,RNA, and DNA methylation solutions
- End-to-end experimental design and optimization
- Expertise in troubleshooting and bioinformatics
- Streamlined workflow for accelerated panel design
Our Expertise
Tailored Solutions to Kickstart your Project
Our Twist Applications Lab provides expert support to help you conduct rapid proof-of-concept studies, optimize assays, and validate experiments. With an in-house lab optimized for high-throughput efficiency, and an expert team of laboratorians, our Applications Lab can advance your project while saving you time.
- High-quality, custom DNA,RNA, and DNA methylation solutions
- End-to-end experimental design and optimization
- Expertise in troubleshooting and bioinformatics
- Streamlined workflow for accelerated panel design
Service Offerings
Comprehensive Lab Services to Support Your Research
Lab Services and Troubleshooting
Full experimental design and protocol troubleshooting with custom samples and analysis options designed to your assay specifications to help solve unique experimental or analytical assay development problems
Panel Testing and Custom Applications
Generate preliminary data using your custom panel to accelerate design optimization
Proof of Concept Pilot Studies
Functional experiment performed with high quality control material to generate proof of concept data
Array of Bioinformatic Analysis Services
Consultative analysis services for an assortment of custom bioinformatic tools to analyze DNA, RNA, and methylation datasets
Access to Various Sequencing Platform Types for Different Applications
Several Twist protocols are agnostic to the many sequencing technologies currently on the market. High quality libraries and enriched material can be generated using Twist protocols to be put on all Illumina sequencing platforms, the Element AVITI and several long read platforms, such as the Nanopore and PacBio instruments.
Operational Details
-
Consultative meeting upon project approval
-
DNA and RNA extraction available
-
Automation use available
-
Low to high sample number projects accepted
-
Turnaround time is approximately 4 to 6 weeks
| Application |
Whole Genome Sequencingor Whole Transcriptome Sequencing |
Target Enrichment(Using Custom Panels or Fixed Panels) |
Methylation Detection |
Viral Detection |
|
*Sample Type |
Pre-extracted Material(cfDNA, FFPE, Cell Line) |
Pre-extracted Material(cfDNA, FFPE, Cell Line) |
Pre-extracted Material(cfDNA, FFPE, Cell Line) |
Pre-extracted Material(Cell Line Blood, Waste Water, Bodily Fluids) |
| Nucleic Acid Type |
DNA | RNA |
DNA | RNA |
DNA |
DNA | RNA |
| Sequencing Platform |
Illumina | Element Pacbio | Nanopore |
Illumina | Element Pacbio | Nanopore |
Illumina | Element |
Illumina | Element |
| Bioinformatics Analysis |
Primary, secondary, and tertiary analysis available. |
|||
*DNA and RNA extraction available as an add-on service
Don’t see your application?
Connect with one of our experts to develop a tailored solution supporting your specialized research needs.
Service Offerings
Comprehensive Lab Services to Support Your Research
Lab Services and Troubleshooting
Full experimental design and protocol troubleshooting with custom samples and analysis options designed to your assay specifications to help solve unique experimental or analytical assay development problems
Panel Testing and Custom Applications
Generate preliminary data using your custom panel to accelerate design optimization
Proof of Concept Pilot Studies
Functional experiment performed with high quality control material to generate proof of concept data
Array of Bioinformatic Analysis Services
Consultative analysis services for an assortment of custom bioinformatic tools to analyze DNA, RNA, and methylation datasets
Access to Various Sequencing Platform Types for Different Applications
Several Twist protocols are agnostic to the many sequencing technologies currently on the market. High quality libraries and enriched material can be generated using Twist protocols to be put on all Illumina sequencing platforms, the Element AVITI and several long read platforms, such as the Nanopore and PacBio instruments.
Operational Details
-
Consultative meeting upon project approval
-
DNA and RNA extraction available
-
Automation use available
-
Low to high sample number projects accepted
-
Turnaround time is approximately 4 to 6 weeks
| Application |
Whole Genome Sequencingor Whole Transcriptome Sequencing |
Target Enrichment(Using Custom Panels or Fixed Panels) |
Methylation Detection |
Viral Detection |
|
*Sample Type |
Pre-extracted Material(cfDNA, FFPE, Cell Line) |
Pre-extracted Material(cfDNA, FFPE, Cell Line) |
Pre-extracted Material(cfDNA, FFPE, Cell Line) |
Pre-extracted Material(Cell Line Blood, Waste Water, Bodily Fluids) |
| Nucleic Acid Type |
DNA | RNA |
DNA | RNA |
DNA |
DNA | RNA |
| Sequencing Platform |
Illumina | Element Pacbio | Nanopore |
Illumina | Element Pacbio | Nanopore |
Illumina | Element |
Illumina | Element |
| Bioinformatics Analysis |
Primary, secondary, and tertiary analysis available. |
|||
*DNA and RNA extraction available as an add-on service
Don’t see your application?
Connect with one of our experts to develop a tailored solution supporting your specialized research needs.
Data-driven Insights
Optimizing Custom Panels
for Precision Research
At Twist, we empower researchers with high-quality data and expert-driven optimization to refine custom panels for enhanced performance and reproducibility.
Custom Panel Optimization
Our iterative design and testing approach improves coverage (dark green) and reduces off target rates (light green) to achieve maximum sensitivity and specificity. By leveraging high-quality genomic material and standardized Twist procedures, we provide consistent, reproducible results that drive confident decision-making.
Advanced Methylation Analysis
Using the Twist Alliance Pan-Cancer Methylation Panel, researchers can distinguish malignant vs. benign breast samples through high-resolution methylation profiling. The clustered heat map (right) highlights differential methylation patterns around transcription start sites (TSS), offering valuable insights for further investigations.
Twist’s expert-driven workflows help accelerate research with gold-standard library preparation and target enrichment solutions, ensuring precision, reliability, and efficiency at every stage.
Data-driven Insights
Optimizing Custom Panels
for Precision Research
At Twist, we empower researchers with high-quality data and expert-driven optimization to refine custom panels for enhanced performance and reproducibility.
Custom Panel Optimization
Our iterative design and testing approach improves coverage (dark green) and reduces off target rates (light green) to achieve maximum sensitivity and specificity. By leveraging high-quality genomic material and standardized Twist procedures, we provide consistent, reproducible results that drive confident decision-making.
Advanced Methylation Analysis
Using the Twist Alliance Pan-Cancer Methylation Panel, researchers can distinguish malignant vs. benign breast samples through high-resolution methylation profiling. The clustered heat map (right) highlights differential methylation patterns around transcription start sites (TSS), offering valuable insights for further investigations.
Twist’s expert-driven workflows help accelerate research with gold-standard library preparation and target enrichment solutions, ensuring precision, reliability, and efficiency at every stage.
Resources & Tools
Access essential tools and documents to streamline your research and optimize your workflows with Twist’s industry-leading solutions.
Resources & Tools
Access essential tools and documents to streamline your research and optimize your workflows with Twist’s industry-leading solutions.
Twist products are for research use only. They are not for use in diagnostic procedures.
Partner with Twist to Advance Your Research
Get in touch to see how our Apps Lab can take on your NGS project.
