We’re writing the future of biologics discovery with a best-in-class platform, our library of phage display libraries (known as the “Library of Libraries”), for hard-to-drug targets.
Our pre-constructed, validated phage display libraries are built using our precision DNA writing technology, allowing us to remove motifs that can lead to downstream manufacturing liabilities and focus only on the applicable sequence space. Twist Biopharma has designed multiple general, naïve, and target-focused libraries with diversities ~1010, giving you a multifaceted approach to your next discovery project.
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Our collection of off-the-shelf libraries enable you to quickly identify high-quality leads against your target of interest using multiple strategies in only a few months. Select from libraries containing naïve human diversity, rationally designed with antibody structural considerations, or with diversity computationally tailored to high-value targets, including carbohydrates, hyperimmune, and structural motifs. They’re available in a variety of VHH, Fab, and scFv frameworks. These libraries can also be leveraged to develop monoclonal antibodies, multi-specifics, and chimeric antigen receptors (CARs) for CAR-T cell therapy.
Twist is the only synthetic DNA provider who can deliver the quantity and quality of DNA we need for our projects rapidly. We are working with them not only as a vendor for synthetic genes and antibodies, but have expanded our relationship to leverage the Twist Biopharma capabilities, which we believe complement our antibody discovery efforts.
Twist Bioscience HQ
681 Gateway Blvd
South San Francisco, CA 94080
Genes
Oligo Pools
NGS
Variant Libraries
Synthetic Controls
Antibody Discovery
IVDR Solutions
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