
Having flexible and cost-effective panels has allowed us to do more samples and go deeper and deeper” to detect those low, low fraction variants
Brendan Blumenstiel
Broad Institute of MIT and Harvard
Achieve superior enrichment efficiency with Twist Bioscience NGS Target Enrichmen Solutions. Targeted sequencing takes a step forward with an optimized enrichment workflow and easy customization of panel content
Our probes enable improved coverage of intended targets when compared to the competition. Improved uniformity increases the percentage of bases covered at the desired depth and reduces the amount of over sequencing.
Uniformity describes the read distribution along target regions of the genome. Uniform coverage reduces the amount of sequencing required to reach a sufficient depth of coverage for all regions of interest. Achieving the sequencing requirement for your application equates to higher confidence in variant detection.
Having flexible and cost-effective panels has allowed us to do more samples and go deeper and deeper” to detect those low, low fraction variants
I heard a rumour of “incredible uniformity” regarding Twist's Target Enrichment tools. We decided to try the Twist Exome to form our own opinions. The rumor was true! Not only was uniformity incredible, but coverage was, as well. Now we use a Twist Custom Panel tailored to the specific requirements of our patients.
Twist Custom Panels allowed us to focus on important, medically relevant genes instead of the whole genome. The panel was concise, with a simple protocol, and the cost reasonable with very good candidate variants already curated by the literature.
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Having flexible and cost-effective panels has allowed us to do more samples and go deeper and deeper” to detect those low, low fraction variants
Brendan Blumenstiel
Broad Institute of MIT and Harvard

I heard a rumour of “incredible uniformity” regarding Twist's Target Enrichment tools. We decided to try the Twist Exome to form our own opinions. The rumor was true! Not only was uniformity incredible, but coverage was, as well. Now we use a Twist Custom Panel tailored to the specific requirements of our patients.
Simon von Ameln, PhD
ÜBAG Dres. Habets / Keller / Groschek / Danaei – Aachen, Germany

Twist Custom Panels allowed us to focus on important, medically relevant genes instead of the whole genome. The panel was concise, with a simple protocol, and the cost reasonable with very good candidate variants already curated by the literature.
Renata Pelligrino, PhD
Children’s Hospital of Philadelphia
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