Twist Bioscience and New England Biolabs (NEB) have partnered to revolutionize methylome analysis. The NEBNext® EM-seq v2 kit for Twist Methylation is a tool for identifying CpG sites without the use of damaging chemical conversion processes. Instead, EM-seq uses a two-step enzymatic conversion process that is less damaging to the DNA, resulting in high-quality libraries that can be sequenced to identify 5mC and 5hmC sites. Coupled with Twist Methylation Panels and Enrichment Kits, the end-to-end system provides unparalleled sequencing efficiency through state-of-the-art enzymology, targeted panel design algorithms, and optimized workflows.

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