Rewriting Cancer's Script: Insights from Saturation Genome Editing

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Presented by
Dr. David J. Adams
Dr. David J. Adams
Senior Group Leader and Interim Head of Cancer, Ageing and Somatic Mutation, Wellcome Sanger Institute

Covered in this Webinar
How NRF2 and KEAP1 variants reprogram cancer cells to resist therapy.
How saturation-seq couples SGE with single-cell transcriptomics to map variant effects at unprecedented resolution.
How functional and clinical data integration enables confident classification of gain-of-function mutations.

Every mutation tells a story — but most remain unread. Join Dr. David Adams from the Wellcome Sanger Institute to explore how cutting-edge functional genomics is transforming our understanding of cancer genetics.

In this live webinar, Dr. Adams will share how saturation genome editing (SGE) and single-cell transcriptomics can reveal which mutations drive tumor growth and treatment resistance — providing a new framework for functional variant classification across oncology.

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