Twist Human Ancient DNA Panel

Language English

Content

The Ancient Human DNA Panel was developed in collaboration with David Reich’s lab at Harvard University for use in studying the genetic variation in ancient DNA specimens, typically extracted from bones and teeth. The panel targets 1.35 million SNPs, which includes as a subset all of the 1.23 million polymorphic sites in the human genome which were originally published in Fu et al. Nature 2015 ensuring compatibility of new data generated using the Twist Human Ancient DNA Panel with published data on many thousands of ancient individuals. This panel enables genome-scale data at significantly reduced sequencing costs compared with shotgun sequencing due to the ability to highly enrich human DNA fragments.

This original panel was optimized using Twist’s double stranded capture probes and hybridization capture reagents resulting in high genome coverage and reduced allelic bias as seen in Rohland, Mallick et al. Genome Research 2022, PMID: 36517229.

For recommendations on assay set-up, please contact Twist Customer Support.

Note: The Twist Alliance Ancient Human DNA Panel - is not ISO-13485 certified

Ordering Information

Twist Alliance Ancient Human DNA Panel

107479                                                                           Twist Alliance Ancient Human DNA Panel - 13 Mb, 12 reactions

106658                                                                           Twist Alliance Ancient Human DNA Panel - 13 Mb, 96 reactions

104562                                                                            Twist High Concentration Mitochondrial Panel, 96 reactions