Genes
Oligo Pools
NGS
Variant Libraries
Antibody Discovery
IVDR Solutions
Twist Bioscience HQ
681 Gateway Blvd
South San Francisco, CA 94080
Built for More: Uniform Coverage, Higher Yields, and Confident Variant Characterization.
Twist TrueAmp Library Preparation delivers consistent, high quality libraries for NGS target enrichment workflows, especially with challenging low input samples. Powered by Twist’s TrueAmp polymerase and optimized for enzymatic fragmentation, this workflow delivers high conversion efficiency, low GC bias, and balanced coverage, supporting accurate variant characterization across challenging genomic regions.
Reliable uniformity across challenging genomic regions
Improved coverage consistency reduces AT- and GC-related dropout, delivering better representation of difficult regions.
High conversion efficiency from low input and degraded samples
High library yields across low input, FFPE, and variable quality samples help preserve precious material by reducing the need for reruns.
High fidelity amplification for confident variant detection
Twist TrueAmp polymerase minimizes amplification induced errors and bias, supporting accurate detection of low VAF variants.
Related workflows and applications
Technical documents
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Simple, transparent ordering for Complex Genes
Testimonials
What our customers have to say
A key part of our work with external partners is keeping to our agreed project delivery timelines. Having a reliable synthesis partner in Twist is a huge factor in the success of this work, as they make it easy to track the progress of my order, deliver genes on time, and actively communicate whenever there is an issue.
A key part of our work with external partners is keeping to our agreed project delivery timelines. Having a reliable synthesis partner in Twist is a huge factor in the success of this work, as they make it easy to track the progress of my order, deliver genes on time, and actively communicate whenever there is an issue.
A key part of our work with external partners is keeping to our agreed project delivery timelines. Having a reliable synthesis partner in Twist is a huge factor in the success of this work, as they make it easy to track the progress of my order, deliver genes on time, and actively communicate whenever there is an issue.
A key part of our work with external partners is keeping to our agreed project delivery timelines. Having a reliable synthesis partner in Twist is a huge factor in the success of this work, as they make it easy to track the progress of my order, deliver genes on time, and actively communicate whenever there is an issue.
A key part of our work with external partners is keeping to our agreed project delivery timelines. Having a reliable synthesis partner in Twist is a huge factor in the success of this work, as they make it easy to track the progress of my order, deliver genes on time, and actively communicate whenever there is an issue.
A key part of our work with external partners is keeping to our agreed project delivery timelines. Having a reliable synthesis partner in Twist is a huge factor in the success of this work, as they make it easy to track the progress of my order, deliver genes on time, and actively communicate whenever there is an issue.
A key part of our work with external partners is keeping to our agreed project delivery timelines. Having a reliable synthesis partner in Twist is a huge factor in the success of this work, as they make it easy to track the progress of my order, deliver genes on time, and actively communicate whenever there is an issue.
A key part of our work with external partners is keeping to our agreed project delivery timelines. Having a reliable synthesis partner in Twist is a huge factor in the success of this work, as they make it easy to track the progress of my order, deliver genes on time, and actively communicate whenever there is an issue.
A key part of our work with external partners is keeping to our agreed project delivery timelines. Having a reliable synthesis partner in Twist is a huge factor in the success of this work, as they make it easy to track the progress of my order, deliver genes on time, and actively communicate whenever there is an issue.
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Genes are just one part of the workflow. Users pair Twist Genes with
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Antibody Production and Characterization Services
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Antibody Production and Characterization Services
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Antibody Production and Characterization Services
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Antibody Production and Characterization Services
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Antibody Production and Characterization Services
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Product data
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Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Figure 1. comparison of enriched libraries with low-input FFPE degraded samples (DIN <2.2) between TrueAmp Library Preparation Kit and competitor K kit, demonstrating the optimal solution for challenging sample applications. (A) The Twist TrueAmp Library Preparation Kit generates superior pre-capture library yield, indicative of high library construction and amplification efficiency. (B) The Twist TrueAmp Library Preparation Kit shows higher library complexity when compared with the competitor’s kits. This allows for more unique DNA molecules that are sequenceable in the library, reducing sequencing costs. (C) Achieves higher coverage.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Figure 1. comparison of enriched libraries with low-input FFPE degraded samples (DIN <2.2) between TrueAmp Library Preparation Kit and competitor K kit, demonstrating the optimal solution for challenging sample applications. (A) The Twist TrueAmp Library Preparation Kit generates superior pre-capture library yield, indicative of high library construction and amplification efficiency. (B) The Twist TrueAmp Library Preparation Kit shows higher library complexity when compared with the competitor’s kits. This allows for more unique DNA molecules that are sequenceable in the library, reducing sequencing costs. (C) Achieves higher coverage.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Video
*For Research Use Only. Not for Diagnostic Procedures.
US manufacturing
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Figure 1. comparison of enriched libraries with low-input FFPE degraded samples (DIN <2.2) between TrueAmp Library Preparation Kit and competitor K kit, demonstrating the optimal solution for challenging sample applications. (A) The Twist TrueAmp Library Preparation Kit generates superior pre-capture library yield, indicative of high library construction and amplification efficiency. (B) The Twist TrueAmp Library Preparation Kit shows higher library complexity when compared with the competitor’s kits. This allows for more unique DNA molecules that are sequenceable in the library, reducing sequencing costs. (C) Achieves higher coverage.
US manufacturing
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Figure 1. comparison of enriched libraries with low-input FFPE degraded samples (DIN <2.2) between TrueAmp Library Preparation Kit and competitor K kit, demonstrating the optimal solution for challenging sample applications. (A) The Twist TrueAmp Library Preparation Kit generates superior pre-capture library yield, indicative of high library construction and amplification efficiency. (B) The Twist TrueAmp Library Preparation Kit shows higher library complexity when compared with the competitor’s kits. This allows for more unique DNA molecules that are sequenceable in the library, reducing sequencing costs. (C) Achieves higher coverage.
US manufacturing
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Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
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US manufacturing
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US manufacturing
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US manufacturing
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Highlighted resources
Case study
GWAS in a Rat Model of Temperament Identifies Multiple Loci for Exploratory Locomotion and Anxiety-Like Traits
Ebook
GWAS in a Rat Model of Temperament Identifies Multiple Loci for Exploratory Locomotion and Anxiety-Like Traits
White paper
GWAS in a Rat Model of Temperament Identifies Multiple Loci for Exploratory Locomotion and Anxiety-Like Traits
Poster
GWAS in a Rat Model of Temperament Identifies Multiple Loci for Exploratory Locomotion and Anxiety-Like Traits
Guide
GWAS in a Rat Model of Temperament Identifies Multiple Loci for Exploratory Locomotion and Anxiety-Like Traits
Webinar
GWAS in a Rat Model of Temperament Identifies Multiple Loci for Exploratory Locomotion and Anxiety-Like Traits
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Product offerings
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TrueAmp Library Preparation Kit
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Library Preparation Solutions
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Library Preparation Solutions
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TrueAmp Library Preparation Kit
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