Identification of Dickkopf-1 (DKK1) Antibodies Utilizing a Multi-Faceted Discovery

Webinar
Presented by
Hoa Giang
Hoa Giang
Product Leader, Biopharma Solutions

Covered in this Webinar
Twist presents a discovery workflow for identifying high-affinity antibodies against Dickkopf-1 (DKK1).
See how to combine synthetic antibody libraries, precision gene synthesis, and high-throughput screening.
Learn how integrated synthetic biology tools can unlock new possibilities for cancer immunotherapy development.

In this presentation from The Landscape of Cancer Research: Advances in Immuno-Oncology, Twist Bioscience highlights a multifaceted approach to antibody discovery targeting Dickkopf-1 (DKK1), a protein implicated in tumor progression and immune evasion. The talk, titled “Identification of Dickkopf-1 (DKK1) Antibodies Utilizing a Multi-Faceted Discovery Strategy,” outlines how Twist’s synthetic DNA and antibody libraries enabled the rapid development of high-affinity antibodies with therapeutic potential.

The presentation showcases how Twist’s platform integrates high-throughput screening, precision gene synthesis, and rational design to accelerate the development of novel immunotherapies. By targeting DKK1—a promising but challenging cancer antigen—Twist demonstrates the power of its end-to-end antibody discovery workflow for advancing immuno-oncology research and supporting the development of next-generation cancer therapies.

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