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App Note

NGS-based Target Capture for SARS-CoV-2 Detection and Characterization

SARS-CoV-2, a single-stranded RNA virus, is the cause of the ongoing pandemic of Coronavirus Disease (COVID-19). Reverse Transcription PCR (RT-PCR) is a rapid method for detecting COVID-19 cases by using primers to amplify regions of interest from the SARS-CoV-2 virus. However, the need exists not only for rapid testing, but also highly sensitive tests capable of characterizing the entire viral genome, including any mutations, to monitor the viral spread and evolution over time.