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Full-gene phasing and no coverage gap in the GBA gene
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Combine Twist target enrichment with long read sequencing to efficiently sequence important genomic regions at scale. Pre-designed Twist Alliance panels enable researchers to capture target regions in a cost-effective and high throughput manner. Customers can also develop fully customizable and scalable panels with their own designs.
Panels Built for Long Read Sequencing Platforms
- Probes optimized for high uniformity and sequencing efficiency
- Balanced coverage across difficult-to-sequence or difficult–to-map regions
- Custom panels with cost-effective and flexible scaling
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Long Read Sequencing at Scale
- Protocols optimized for long fragment enrichment
- Pack more samples in a single sequencing run
- Study targeted regions across large cohorts
Accurate Variant Calling
- High accuracy variant calling of SNPs, SVs and indels
- Unambiguous haplotype resolution and long-range phasing
- Compatible with both Oxford Nanopore and PacBio long read platforms
Twist Alliance Dark Genes Panel
Enables sequencing of genes that are difficult or impossible to fully sequence with short read technology.
- Targets 389 genes (20 Mb)
- Key targets include GBA, SMN1/2
Twist Alliance Long-Read PGx Panel
Focus on important genes in pharmacogenomics that are critical to drug metabolism and patient therapeutic response.
- Targets 49 genes (2 Mb)
- Key targets include CYP2D6, HLA-A, HLA-B
Accurate star allele calling at CYP2D6
PRODUCT SKUS
106747
Twist Alliance Dark Genes Panel, 2 Reaction Kit
106748
Twist Alliance Dark Genes Panel, 12 Reaction Kit
106914
Twist Alliance Dark Genes Panel, 96 Reaction Kit
106749
Twist Alliance Long-Read PGx Panel, 2 Reaction Kit
106750
Twist Alliance Long-Read PGx Panel, 12 Reaction Kit
106915
Twist Alliance Long-Read PGx Panel, 96 Reaction Kit
Long-read capture with Twist target enrichment system
Long Read Library Preparation and Standard Hyb v2 Enrichment
Long-Read Capture with Twist Target Enrichment
Twist Bioscience HQ
681 Gateway Blvd
South San Francisco, CA 94080
